• Time:
    15/12/2026–26/02/2027
  • Price:
    free
  • Volume:
    2 ECTS (52 hours)
  • Location:
    Online
  • Language of instruction:
    English
  • Form of study:
    Online learning
  • Document issued:
    Certificate of completion
Register
  • Time:
    15/12/2026–26/02/2027
  • Price:
    free
  • Volume:
    2 ECTS (52 hours)
  • Location:
    Online
  • Language of instruction:
    English
  • Form of study:
    Online learning
  • Document issued:
    Certificate of completion
  • Objective:
    To offer comprehensive knowledge and skills in LC-MS Methods Validation.

  • Target group:
    All who have preliminary knowledge about analytical chemistry, liquid chromatograpy and mass spectrometry.
  • Learning outcomes:
    The participant who has successfully passed the course knows:
    - the main performance parameters of analytical methods, what they show and which of them are particularly important in different situations;
    - the main mathematical concepts and tools in method validation;
    - the main approaches for evaluation of the performance parameters in the case of LC/MS analysis.
    The participant who has successfully passed the course is able to:
    - decide what data are needed for evaluating the different method performance parameters, understand the meaning of the available data and decide whether the available data are sufficient;
    - select the approach and design the experiments for obtaining suitable data;
    - quantify the relevant performance parameters using the available data and assess whether the obtained values are realistic;
    - assess the fitness of the method for the intended purpose based on the values of the evaluated performance parameters.
  • Lecturers:
    Ivo Leito
    Koit Herodes
    Karin Kipper
    Riin Rebane
    Irja Helm
    Asko Laaniste
    Hanno Evard
  • Content:
    Topic Credit Lectors
    1. Practice-oriented on-line course on validation of analytical methods, specifically using LC-MS as technique.
    The course covered the following topics:
    - The concept, workflow and scope of validation;
    - Selectivity and identity confirmation, both via LC and via MS;
    - Linearity of signal, linear range, sensitivity and their relation to calibration;
    - Precision, trueness, accuracy, analyte stability and their interrelations;
    - Limit of detection and limit of quantitation;
    - Ruggedness and robustness.    		 52 Ivo Leito, Koit Herodes, Karin Kipper, Riin Rebane, Irja Helm, Asko Laaniste, Hanno Evard

  • Study programme group:
    Chemistry
  • Programme code:
    P2AV.TK.829
  • Completion requirements:
    Passing all graded tests with at least 50% of the maximum score.
  • Mode of assessment of achieving learning outcomes:
    differentiated (A, B, C, D, E, F, not present)
  • Assessment methods:
    tests
  • Assessment criteria:
    Passing all graded tests with at least 50% of the maximum score. Read more from course introduction in Moodle: https://moodle.ut.ee/mod/page/view.php?id=270849
  • Venue info
    Web-based course in Moodle.
  • Schedule:
    According to the action plan in Moodle. There are no live lectures.
    For every week a set of tasks will be given.
    At the end of each week there will be a graded test (in the Moodle environment).
  • Description of learning environment:
    Web-based course in Moodle.
  • Price:
    free
  • Price info:
    Free MOOC
    The students who have successfully passed the course will be issued a certificate of completion by the University of Tartu.
    A digital certificate of completion is free of charge. Please read the technical requirements for downloading and opening the digitally verified document: https://ut.ee/en/digital-continuing-education-certificates

    A certificate of completion on paper can be requested for a fee of 62 euros (incl. all taxes). The basis of payment for the certificate on paper is the invoice issued by the university. The certificate will be sent out after the receipt of payment.

    If you would like to get a paper certificate, please provide us with this information before the end of the course by e-mail: [email protected].
  • Income tax reimbursement to natural person:
    No
  • Additional information about registration:
    Please enter the correct full name and date of birth during registration.They go on the final document.
  • Further information:
    Esta Pilt, [email protected], +372 737 5560
Register
Register
Register
Esta Pilt
Office of Academic Affairs
Lifelong Learning Centre
Programme Director for Continuing Education
online continuing education, summer and winter university
+372 737 5560
+372 522 8028 (5560)
Ülikooli 18–234B
General contact for continuing education
Lifelong Learning Centre
+372 737 6213
Ülikooli 18, Tartu, 50090

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